I just started using NuSphere phpED because it’s better suited for working with PHP then Dreamweaver. But one problem I had was that I couldn’t find an option that would make it upload a file to the server (Through FTP/etc.) whenever I saved it.
So I asked around a little and it seems there’s a keyboard shortcut that does this (Shift+Ctrl+S), But I can imagine you want this behaviour to be default on Ctrl+S (Well I do.).
First go to Tools -> Settings
Then in the options menu go to IDE -> IDE Shortcuts
Then scroll down till you find Upload File(s)
Then change the shortcut to Ctrl+S
It will ask to cancel because there’s already a shortcut assigned to it, Just click no.
Now do the same for the shortcut File -> Save and assign it to Ctrl+Shift+S